About

Are you interested in taking your knowledge of the biomedical sciences to a higher level? Do you want to earn a PhD to expand your career possibilities?

The Brody School of Medicine at East Carolina University offers a doctor of philosophy in biomedical sciences. The program is housed in the BSOM Office of Research and Graduate Studies. Students select an area of concentration in anatomy, biochemistry, microbiology and immunology, pharmacology, and physiology.

For exceptionally well-prepared students, some of the core competencies can be waived. If fewer than 76 s. h. of course work and cognates to the major field are required in a plan, a specific statement to justify this plan should be submitted to, and approved by, the program director and the dean of the Graduate School.

In addition to course requirements, students are encouraged to participate in scholarly activities, such as experience as teaching assistants and involvement in university-wide seminars. Such activities should be considered as components of the overall program of study.

ECU Advantage

Departmental laboratories are equipped with state-of-the art instruments. In addition, the Brody School of Medicine has established several core laboratories to support the research efforts of all faculty members. These include an Electron Microscope Laboratory, a Flow Cytometry Laboratory, a Hybridoma Core Laboratory, Molecular Biology Reagent Program, a Peptide Microsequencing Laboratory, a Phosphoimaging Laboratory, and modern animal laboratories.

As part of their predissertation course requirements, students are assigned various periods of rotation in research laboratories of individual faculty members to gain perspectives and laboratory experience. Assignment of students to individual faculty members for predissertation rotations are made in conjunction with the chairperson, the student's advisory committee, and concentration director.

As an ECU student, you can research your future career in Steppingblocks. Explore real-world stats about your major, your interests, and your dream job title with data-powered career exploration tools designed for doers like you.

What You Will Study

Program Coordinator: Richard A. Franklin (4N84A Brody School of Medicine; 252-744-3305; franklinr@ecu.edu)

The Brody School of Medicine (BSOM) at East Carolina University (ECU) offers a doctor of philosophy (PhD) in biomedical sciences. The program is housed in the BSOM Office of Research and Graduate Studies. Students select an area of concentration in anatomy and cell biology; biochemistry and molecular biology; integrative physiology and metabolism; microbiology and immunology; or pharmacology and toxicology.

For exceptionally well-prepared students some of the core competencies can be waived. If fewer than 76 s. h. of coursework and cognates to the major field are required in a plan, a specific statement to justify this plan should be submitted to, and approved by, the program director and the dean of the Graduate School.

The Biomedical Sciences, PhD requires a minimum of 76 s. h. as follows:

1. General core - 9 s.h.
  • BIOS 7021 - Biostatistics for Health Professionals I
  • OR
  • PHAR 7777 - Practical Problems in Biometry

  • HUMS 7004 - Ethics and Research
  • Seminars - 4 s.h. total
2. Concentrations - 36-38 s.h.

Electives must be chosen in consultation with the Graduate Advisory Committee and concentration director. Select one of the following concentrations.

    a. Anatomy and cell biology
    • ANAT 7202 - Molecular Cell Biology
    • ANAT 7365 - Research Proposal Strategies

    • ANAT 7210 - Histology and Cell Biology
    • OR
    • BIOC 7301 - Biochemistry I

    • Electives to meet minimum concentration requirement
    b. Biochemistry and molecular biology
    • BIOC 7310 - Molecular Biochemistry
    • BIOC 7365 - Research Proposal Strategies
    • BIOC 8320 - Biochemistry II: Regulation of Metabolism

    • BIOC 8333 - Research
    • OR
    • BIOC 8336 - Research

    • Electives totaling at least 13-16 s.h.
    c. Integrative physiology and metabolism
    • PHLY 7701 - Graduate Physiology I
    • PHLY 7702 - Graduate Physiology II
    • PHLY 7705 - Critical Thinking in Physiology

    • Electives to meet minimum concentration requirement
    d. Microbiology and immunology
    • BIOC 7301 - Biochemistry I
    • MCBI 7002 - Medical Immunology
    • MCBI 7003 - Medical Virology
    • MCBI 7004 - Medical Microbiology
    • MCBI 7410 - Molecular Cell Biology
    • MCBI 7490 - Topics in Microbiology and Immunology

    • MCBI 7420 - Physiology and Ultrastructure of Microorganisms I
    • OR
    • MCBI 7450 - Immunology
    • OR
    • MCBI 7460 - Advanced Virology

    • Electives to meet minimum concentration requirement
    e. Pharmacology and toxicology
    • BIOC 7310 - Molecular Biochemistry
    • PHAR 7606 - Integrative Pharmacology and Toxicology I: ​An Organ Systems Approach​
    • PHAR 7607 - Integrative Pharmacology and Toxicology II: ​ A Molecular and Cellular Approach​
    • PHAR 7609 - Introduction to Pharmacology
    • PHAR 7610 - Mechanisms of Drug Action
    • PHAR 7611 - Current Topics in Pharmacology and Toxicology
    • PHAR 7614 - Research Procedures I
    • PHAR 7615 - Research Procedures II
    • PHAR 7680 - Toxicology
    • PHAR 7682 - Advanced Toxicology

    • Electives to meet minimum concentration requirement
3. Research Core - 29-31 s.h.
    a. Laboratory research (2-4 s.h.)

    (ANAT 7240 or BIOC 7330 or MCBI 7498 or PHAR 7614 or PHLY 7740)

      b. Research dissertation (27 s.h.)

      (ANAT 9000 or BIOC 9000 or MCBI 9000 or PHAR 9000 or PHLY 9000)

      Admission

      Admission to study at the doctoral level requires acceptance by the ECU Graduate School and the BSOM Office of Research and Graduate Studies. The application for admission to the Graduate School and official transcripts from each college or university attended must be sent to the Graduate School.

      A student whose undergraduate transcript indicates a deficiency in program prerequisites may be required to undergo examination to verify competency before admission to graduate study.  If a student is admitted deficient in analytical and communicative skills necessary for his or her anticipated program, specific remediation will be prescribed in the student's individual program plan. All such deficiencies must be removed before the doctoral candidacy examination is administered.

        Doctoral Candidacy Examination

        This examination is normally taken after the major course requirements have been completed. Upon passing this examination, the student is admitted to candidacy for the degree, doctor of philosophy. Each candidate is examined for his or her understanding and mastery of a broad field of knowledge, abilities for critical analysis and synthesis, as well as a familiarity with scholarly methods of research. The examination of scientific material shall consist of written and oral components. At the option of the concentration, a major part of the examination format may be the defense of an original proposal developed by the student.

          Doctoral Dissertation

          The dissertation must reflect independent, self-motivated research which contributes significant new knowledge to the candidate's major field. The dissertation should demonstrate the candidate's skills in experimental design and technique. It must be clearly written and demonstrate understanding of the historical foundations of the work as well as a thorough analysis of the strengths, weaknesses, and significance of the results.

            Student Advisory Committee

            The concentration director will be responsible for designing tentative program plans for all entering students and for evaluating their performance until the individual advisory committee is established.

              Time Limits for Completion of Degree Requirements

              A doctoral degree program should be completed before the end of the twelfth semester, excluding summers, following initial enrollment. With endorsement of the student's advisory committee and the departmental chairperson in which the student dissertation director resides, a student may request an extension.  Dissertation credits used toward a degree in one concentration cannot be subsequently applied to earn a degree in a second concentration.

                Transfer Credits

                Graduate work completed prior to admission to doctoral candidacy will be evaluated by the concentration director when the individual program of study is developed.  Transfer of credit from another university is subject to further approval by the concentration director, program director, and the dean of the Graduate School.

                  Other

                  In addition to course requirements, students are encouraged to participate in scholarly activities, such as experience as teaching assistants and involvement in university-wide seminars. Such activities should be considered as components of the overall program of study.

                  As part of their predissertation course requirements, students are assigned various periods of rotation in research laboratories of individual faculty members to gain perspectives and laboratory experience.  Assignment of students to individual faculty members for predissertation rotations are made in conjunction with the chairperson, the student's advisory committee, and concentration director.

                    For more information about this degree visit the university's academic catalogs.